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    Re: New article - mold biotoxins cause non-allergic reaction

    Posted by deborah on 1/15/10

    I still cannot find that article, did find the journal, but not
    that article.

    Did find a very interesting one there...

    Assessment Of Neuromuscular Dysfunction During Poisoning By
    Organophosphorus Compounds

    Horst Thiermanna, The Corresponding Author, Thomas Seegera, Sascha
    Gondera, Nadja Herkerta, Bernd Antkowiakb, Thomas Zilkerc, Florian
    Eyerc and Franz Woreka


    Dysfunction of respiratory muscles is a life-threatening
    complication in poisoning by organophosphorus compounds (OP). It
    is both of central and peripheral origin due to impaired
    cholinergic signalling upon inhibition of acetylcholinesterase
    (AChE). The dysfunction at neuromuscular synapses is not amenable
    to anticholinergics and remains a therapeutic challenge. Thus, a
    clear understanding of the distinct mechanisms occurring at
    neuromuscular synapses is decisive for the development and
    improvement of therapeutic strategies, particularly with nerve
    agent poisoning, where clinical studies are prevented by ethical

    On 1/15/10, Deborah wrote:
    > On 1/11/10, Deborah wrote:
    >> JF,
    >> Were you able to find it online somewhere?
    >> On 1/09/10, Deborah wrote:
    >>> Thanks!
    >>> On 1/09/10, JF wrote:
    >>>> Here's another new article showing non-allergenic health
    >>>> effects of mold biotoxins. The truth is coming out,
    >>>> slowly but surely:
    >>>> Inflammation-associated gene transcription and expression
    >>>> in mouse lungs induced by low molecular weight compounds
    >>>> from fungi from the built environment.
    >>>> J.D. Millera, M. Sunb, A. Gilyanb, J. Royb and T.G. Randb,
    >>>> Chemico-Biological Interactions
    >>>> Volume 183, Issue 1, January 2010, Pages 113-124
    >>>> "The transcriptional regulation in these genes in the
    >>>> treatment groups suggests that they may serve central
    >>>> roles in the immunomodulation of toxin-induced pro-
    >>>> inflammatory lung responses. . . The results further
    >>>> confirm the inflammatory nature of metabolites/toxins from
    >>>> such fungi can contribute to the development of non-
    >>>> allergenic respiratory health effects."

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