Re: New article - mold biotoxins cause non-allergic reaction
Posted by H on 1/17/10
Found the abstract through Medscape:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T56-4XDCHR3-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e502a37ad3547538e83e641ef50c253f
On 1/15/10, deborah wrote:
> I still cannot find that article, did find the journal, but not
> that article.
>
> Did find a very interesting one there...
>
> Assessment Of Neuromuscular Dysfunction During Poisoning By
> Organophosphorus Compounds
>
> Horst Thiermanna, The Corresponding Author, Thomas Seegera, Sascha
> Gondera, Nadja Herkerta, Bernd Antkowiakb, Thomas Zilkerc, Florian
> Eyerc and Franz Woreka
>
> Abstract
>
> Dysfunction of respiratory muscles is a life-threatening
> complication in poisoning by organophosphorus compounds (OP). It
> is both of central and peripheral origin due to impaired
> cholinergic signalling upon inhibition of acetylcholinesterase
> (AChE). The dysfunction at neuromuscular synapses is not amenable
> to anticholinergics and remains a therapeutic challenge. Thus, a
> clear understanding of the distinct mechanisms occurring at
> neuromuscular synapses is decisive for the development and
> improvement of therapeutic strategies, particularly with nerve
> agent poisoning, where clinical studies are prevented by ethical
> considerations.
>
>
> On 1/15/10, Deborah wrote:
>> On 1/11/10, Deborah wrote:
>>> JF,
>>>
>>> Were you able to find it online somewhere?
>>>
>>>
>>>
>>> On 1/09/10, Deborah wrote:
>>>> Thanks!
>>>>
>>>>
>>>>
>>>>
>>>> On 1/09/10, JF wrote:
>>>>> Here's another new article showing non-allergenic health
>>>>> effects of mold biotoxins. The truth is coming out,
>>>>> slowly but surely:
>>>>>
>>>>> Inflammation-associated gene transcription and expression
>>>>> in mouse lungs induced by low molecular weight compounds
>>>>> from fungi from the built environment.
>>>>> J.D. Millera, M. Sunb, A. Gilyanb, J. Royb and T.G. Randb,
>>>>> Chemico-Biological Interactions
>>>>> Volume 183, Issue 1, January 2010, Pages 113-124
>>>>>
>>>>> "The transcriptional regulation in these genes in the
>>>>> treatment groups suggests that they may serve central
>>>>> roles in the immunomodulation of toxin-induced pro-
>>>>> inflammatory lung responses. . . The results further
>>>>> confirm the inflammatory nature of metabolites/toxins from
>>>>> such fungi can contribute to the development of non-
>>>>> allergenic respiratory health effects."
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