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    Re: New article - mold biotoxins cause non-allergic reaction

    Posted by Deborah on 1/17/10

    Thanks, already found it, was looking for entire article.

    On 1/17/10, H wrote:
    > Found the abstract through Medscape:
    >
    http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T56-4XDCHR3-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e502a37ad3547538e83e641ef50c253f
    >
    > On 1/15/10, deborah wrote:
    >> I still cannot find that article, did find the journal, but not
    >> that article.
    >>
    >> Did find a very interesting one there...
    >>
    >> Assessment Of Neuromuscular Dysfunction During Poisoning By
    >> Organophosphorus Compounds
    >>
    >> Horst Thiermanna, The Corresponding Author, Thomas Seegera, Sascha
    >> Gondera, Nadja Herkerta, Bernd Antkowiakb, Thomas Zilkerc, Florian
    >> Eyerc and Franz Woreka
    >>
    >> Abstract
    >>
    >> Dysfunction of respiratory muscles is a life-threatening
    >> complication in poisoning by organophosphorus compounds (OP). It
    >> is both of central and peripheral origin due to impaired
    >> cholinergic signalling upon inhibition of acetylcholinesterase
    >> (AChE). The dysfunction at neuromuscular synapses is not amenable
    >> to anticholinergics and remains a therapeutic challenge. Thus, a
    >> clear understanding of the distinct mechanisms occurring at
    >> neuromuscular synapses is decisive for the development and
    >> improvement of therapeutic strategies, particularly with nerve
    >> agent poisoning, where clinical studies are prevented by ethical
    >> considerations.
    >>
    >>
    >> On 1/15/10, Deborah wrote:
    >>> On 1/11/10, Deborah wrote:
    >>>> JF,
    >>>>
    >>>> Were you able to find it online somewhere?
    >>>>
    >>>>
    >>>>
    >>>> On 1/09/10, Deborah wrote:
    >>>>> Thanks!
    >>>>>
    >>>>>
    >>>>>
    >>>>>
    >>>>> On 1/09/10, JF wrote:
    >>>>>> Here's another new article showing non-allergenic health
    >>>>>> effects of mold biotoxins. The truth is coming out,
    >>>>>> slowly but surely:
    >>>>>>
    >>>>>> Inflammation-associated gene transcription and expression
    >>>>>> in mouse lungs induced by low molecular weight compounds
    >>>>>> from fungi from the built environment.
    >>>>>> J.D. Millera, M. Sunb, A. Gilyanb, J. Royb and T.G. Randb,
    >>>>>> Chemico-Biological Interactions
    >>>>>> Volume 183, Issue 1, January 2010, Pages 113-124
    >>>>>>
    >>>>>> "The transcriptional regulation in these genes in the
    >>>>>> treatment groups suggests that they may serve central
    >>>>>> roles in the immunomodulation of toxin-induced pro-
    >>>>>> inflammatory lung responses. . . The results further
    >>>>>> confirm the inflammatory nature of metabolites/toxins from
    >>>>>> such fungi can contribute to the development of non-
    >>>>>> allergenic respiratory health effects."

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