Re: New article - mold biotoxins cause non-allergic reaction
Posted by Deborah on 1/17/10
Thanks, already found it, was looking for entire article.
On 1/17/10, H wrote:
> Found the abstract through Medscape:
>
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T56-4XDCHR3-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e502a37ad3547538e83e641ef50c253f
>
> On 1/15/10, deborah wrote:
>> I still cannot find that article, did find the journal, but not
>> that article.
>>
>> Did find a very interesting one there...
>>
>> Assessment Of Neuromuscular Dysfunction During Poisoning By
>> Organophosphorus Compounds
>>
>> Horst Thiermanna, The Corresponding Author, Thomas Seegera, Sascha
>> Gondera, Nadja Herkerta, Bernd Antkowiakb, Thomas Zilkerc, Florian
>> Eyerc and Franz Woreka
>>
>> Abstract
>>
>> Dysfunction of respiratory muscles is a life-threatening
>> complication in poisoning by organophosphorus compounds (OP). It
>> is both of central and peripheral origin due to impaired
>> cholinergic signalling upon inhibition of acetylcholinesterase
>> (AChE). The dysfunction at neuromuscular synapses is not amenable
>> to anticholinergics and remains a therapeutic challenge. Thus, a
>> clear understanding of the distinct mechanisms occurring at
>> neuromuscular synapses is decisive for the development and
>> improvement of therapeutic strategies, particularly with nerve
>> agent poisoning, where clinical studies are prevented by ethical
>> considerations.
>>
>>
>> On 1/15/10, Deborah wrote:
>>> On 1/11/10, Deborah wrote:
>>>> JF,
>>>>
>>>> Were you able to find it online somewhere?
>>>>
>>>>
>>>>
>>>> On 1/09/10, Deborah wrote:
>>>>> Thanks!
>>>>>
>>>>>
>>>>>
>>>>>
>>>>> On 1/09/10, JF wrote:
>>>>>> Here's another new article showing non-allergenic health
>>>>>> effects of mold biotoxins. The truth is coming out,
>>>>>> slowly but surely:
>>>>>>
>>>>>> Inflammation-associated gene transcription and expression
>>>>>> in mouse lungs induced by low molecular weight compounds
>>>>>> from fungi from the built environment.
>>>>>> J.D. Millera, M. Sunb, A. Gilyanb, J. Royb and T.G. Randb,
>>>>>> Chemico-Biological Interactions
>>>>>> Volume 183, Issue 1, January 2010, Pages 113-124
>>>>>>
>>>>>> "The transcriptional regulation in these genes in the
>>>>>> treatment groups suggests that they may serve central
>>>>>> roles in the immunomodulation of toxin-induced pro-
>>>>>> inflammatory lung responses. . . The results further
>>>>>> confirm the inflammatory nature of metabolites/toxins from
>>>>>> such fungi can contribute to the development of non-
>>>>>> allergenic respiratory health effects."
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