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    Re: New article - mold biotoxins cause non-allergic reaction

    Posted by Deborah on 1/21/10

    Thanks. Finally figured that out and tracked it down.


    On 1/19/10, JF wrote:
    > Like most scholarly journals, it requires a subscription in order to
    > access it. Academic libraries might subscribe, though many journals
    from
    > this publisher (Reed Elsevier) are very expensive, so they're generally
    > only available at wealthier colleges that have large science programs.
    >
    >
    > On 1/17/10, Deborah wrote:
    >> Thanks, already found it, was looking for entire article.
    >>
    >> On 1/17/10, H wrote:
    >>> Found the abstract through Medscape:
    >>>
    >> http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T56-4XDCHR3-
    >
    1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C00
    >
    0050221&_version=1&_urlVersion=0&_userid=10&md5=e502a37ad3547538e83e641ef5
    > 0c253f
    >>>
    >>> On 1/15/10, deborah wrote:
    >>>> I still cannot find that article, did find the journal, but not
    >>>> that article.
    >>>>
    >>>> Did find a very interesting one there...
    >>>>
    >>>> Assessment Of Neuromuscular Dysfunction During Poisoning By
    >>>> Organophosphorus Compounds
    >>>>
    >>>> Horst Thiermanna, The Corresponding Author, Thomas Seegera, Sascha
    >>>> Gondera, Nadja Herkerta, Bernd Antkowiakb, Thomas Zilkerc, Florian
    >>>> Eyerc and Franz Woreka
    >>>>
    >>>> Abstract
    >>>>
    >>>> Dysfunction of respiratory muscles is a life-threatening
    >>>> complication in poisoning by organophosphorus compounds (OP). It
    >>>> is both of central and peripheral origin due to impaired
    >>>> cholinergic signalling upon inhibition of acetylcholinesterase
    >>>> (AChE). The dysfunction at neuromuscular synapses is not amenable
    >>>> to anticholinergics and remains a therapeutic challenge. Thus, a
    >>>> clear understanding of the distinct mechanisms occurring at
    >>>> neuromuscular synapses is decisive for the development and
    >>>> improvement of therapeutic strategies, particularly with nerve
    >>>> agent poisoning, where clinical studies are prevented by ethical
    >>>> considerations.
    >>>>
    >>>>
    >>>> On 1/15/10, Deborah wrote:
    >>>>> On 1/11/10, Deborah wrote:
    >>>>>> JF,
    >>>>>>
    >>>>>> Were you able to find it online somewhere?
    >>>>>>
    >>>>>>
    >>>>>>
    >>>>>> On 1/09/10, Deborah wrote:
    >>>>>>> Thanks!
    >>>>>>>
    >>>>>>>
    >>>>>>>
    >>>>>>>
    >>>>>>> On 1/09/10, JF wrote:
    >>>>>>>> Here's another new article showing non-allergenic health
    >>>>>>>> effects of mold biotoxins. The truth is coming out,
    >>>>>>>> slowly but surely:
    >>>>>>>>
    >>>>>>>> Inflammation-associated gene transcription and expression
    >>>>>>>> in mouse lungs induced by low molecular weight compounds
    >>>>>>>> from fungi from the built environment.
    >>>>>>>> J.D. Millera, M. Sunb, A. Gilyanb, J. Royb and T.G. Randb,
    >>>>>>>> Chemico-Biological Interactions
    >>>>>>>> Volume 183, Issue 1, January 2010, Pages 113-124
    >>>>>>>>
    >>>>>>>> "The transcriptional regulation in these genes in the
    >>>>>>>> treatment groups suggests that they may serve central
    >>>>>>>> roles in the immunomodulation of toxin-induced pro-
    >>>>>>>> inflammatory lung responses. . . The results further
    >>>>>>>> confirm the inflammatory nature of metabolites/toxins from
    >>>>>>>> such fungi can contribute to the development of non-
    >>>>>>>> allergenic respiratory health effects."

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