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    Post: Toxicology of mycotoxins

    Posted by Sharon on 3/14/10

    springer link. c o m / content / px 32071j 1517731 6 /

    "Toxicology of mycotoxins
    Robert R. M. Paterson1 and Nelson Lima1

    Centre of Biological Engineering, IBB-Institute for
    Biotechnology and Bioengineering, Universidade do Minho,
    Braga, Portugal

    Humans are exposed to mycotoxins via ingestion, contact and
    inhalation. This must have occurred throughout human
    history and led to severe outbreaks. Potential diseases
    range from akakabio-byo to stachybotryotoxicosis and
    cancer. The known molecular bases of toxicology run the
    gamut of 23 compounds, from aflatoxins (AFs) to
    zearalenone, ochratoxin A and deoxynivalenol. Ergotism is
    one of the oldest recognized mycotoxicosis, although
    mycotoxin science only commenced in the 1960s with the
    discovery of AFs in turkey feed. AFs are carcinogenic. Some
    others are suspected carcinogens. The effects of mycotoxins
    are acute or chronic in nature. Mycotoxins are well known
    in the scientific community, although they have a low
    profile in the general population. An incongruous situation
    occurs in United States where mycotoxins from “moldy homes”
    are considered to be a significant problem, although there
    is a general debate about seriousness. This contrasts with
    the thousands of deaths from mycotoxins that occur, even
    now, in the technologically less developed countries (e.g.,
    Indonesia, China, and Africa). Mycotoxins are more toxic
    than pesticides. Studies are moving from whole animal work
    to investigating the biochemical mechanisms in isolated
    cells, and the mechanisms of toxicity at the molecular
    level are being elucidated. The stereochemical nature of
    AFs has been shown to be important. In addition, the effect
    of multiple mycotoxins is being increasingly investigated,
    which will more accurately represent the situation in
    nature. It is anticipated that more fungal metabolites will
    be recognized as dangerous toxins and permitted statutory
    levels will decrease in the future."

    Gee. Guess the US Chamber of Commerce Institute for Legal
    Reform, the Manhattan Institute Center for Legal Policy,
    and the little cabal of Big Tobacco White Coats turned self
    professed mold "experts" circa 2000, were wrong that it has
    been scientifically proven all claims of illness from the
    toxins of mold are only being made because of "trial
    lawyers, media and junk science".

    Just spent some time on an ecoexcursion.
    ignacio springs . co m /

    Amazing how such a break can renew one's spirit and ability
    to rock and roll in the name of accurate US public health
    policy marketing!

    Posts on this thread, including this one

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