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    Post: Relationshipsrhinitis, fibromyalgia, and chronic fatigue

    Posted by Sharon on 6/21/10

    Relationships among rhinitis, fibromyalgia, and chronic

    Authors: Baraniuk, James N.; Zheng, Yin

    Source: Allergy and Asthma Proceedings, Volume 31, Number
    3, May/June 2010 , pp. 169-178(10)

    Publisher: OceanSide Publications, Inc

    Allergy and Asthma Proceedings is a peer reviewed
    publication dedicated to distributing timely scientific
    research regarding advancements in the knowledge and
    practice of allergy, asthma and immunology. Its primary
    readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a
    predominantly clinical focus which directly impact quality
    of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food
    allergies, allergic skin diseases, diagnostic techniques,
    allergens, and treatment modalities. Published material
    includes peer-reviewed original research, clinical trials
    and review articles.

    New information about the pathophysiology of idiopathic
    nonallergic rhinopathy indicates a high prevalence in
    chronic fatigue syndrome (CFS). This article shows the
    relevance of CFS and allied disorders to allergy practice.
    CFS has significant overlap with systemic hyperalgesia
    (fibromyalgia), autonomic dysfunction (irritable bowel
    syndrome and migraine headaches), sensory hypersensitivity
    (dyspnea; congestion; rhinorrhea; and appreciation of
    visceral nociception in the esophagus, gastrointestinal
    tract, bladder, and other organs), and central nervous
    system maladaptations (central sensitization) recorded by
    functional magnetic resonance imaging (fMRI). Neurological
    dysfunction may account for the overlap of CFS with
    idiopathic nonallergic rhinopathy. Scientific advances are
    in fMRI, nociceptive sensor expression, and, potentially,
    infection with xenotropic murine leukemia-related virus
    provide additional insights to novel pathophysiological
    mechanisms of the “functional” complaints of these patients
    that are mistakenly interpreted as allergic syndromes. As
    allergists, we must accept the clinical challenges posed by
    these complex patients and provide proper diagnoses,
    assurance, and optimum care even though current treatment
    algorithms are lacking.
    Keywords: Central sensitization; CFS; chronic fatigue
    syndrome; dysautonomia; fatigue; fibromyalgia; idiopathic
    nonallergic rhinitis; pain; xenotropic murine leukemia-
    related virus; XMRV

    Document Type: Research article

    DOI: 10.2500/aap.2010.31.3311

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