Re: Relationshipsrhinitis, fibromyalgia, and chronic fatigue
Posted by Deborah on 6/23/10
Good one. Thanks, Sharon. On 6/21/10, Sharon wrote: > Relationships among rhinitis, fibromyalgia, and chronic > fatigue > > http://www.ingentaconnect.com/content/ocean/aap/2010/0000003 > 1/00000003/art00002 > > Authors: Baraniuk, James N.; Zheng, Yin > > Source: Allergy and Asthma Proceedings, Volume 31, Number > 3, May/June 2010 , pp. 169-178(10) > > Publisher: OceanSide Publications, Inc > > > Allergy and Asthma Proceedings is a peer reviewed > publication dedicated to distributing timely scientific > research regarding advancements in the knowledge and > practice of allergy, asthma and immunology. Its primary > readership consists of allergists and pulmonologists. > > The goal of the Proceedings is to publish articles with a > predominantly clinical focus which directly impact quality > of care for patients with allergic disease and asthma. > > Featured topics include asthma, rhinitis, sinusitis, food > allergies, allergic skin diseases, diagnostic techniques, > allergens, and treatment modalities. Published material > includes peer-reviewed original research, clinical trials > and review articles. > Abstract: > > New information about the pathophysiology of idiopathic > nonallergic rhinopathy indicates a high prevalence in > chronic fatigue syndrome (CFS). This article shows the > relevance of CFS and allied disorders to allergy practice. > CFS has significant overlap with systemic hyperalgesia > (fibromyalgia), autonomic dysfunction (irritable bowel > syndrome and migraine headaches), sensory hypersensitivity > (dyspnea; congestion; rhinorrhea; and appreciation of > visceral nociception in the esophagus, gastrointestinal > tract, bladder, and other organs), and central nervous > system maladaptations (central sensitization) recorded by > functional magnetic resonance imaging (fMRI). Neurological > dysfunction may account for the overlap of CFS with > idiopathic nonallergic rhinopathy. Scientific advances are > in fMRI, nociceptive sensor expression, and, potentially, > infection with xenotropic murine leukemia-related virus > provide additional insights to novel pathophysiological > mechanisms of the “functional” complaints of these patients > that are mistakenly interpreted as allergic syndromes. As > allergists, we must accept the clinical challenges posed by > these complex patients and provide proper diagnoses, > assurance, and optimum care even though current treatment > algorithms are lacking. > Keywords: Central sensitization; CFS; chronic fatigue > syndrome; dysautonomia; fatigue; fibromyalgia; idiopathic > nonallergic rhinitis; pain; xenotropic murine leukemia- > related virus; XMRV > > Document Type: Research article > > DOI: 10.2500/aap.2010.31.3311
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