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    Re: Relationshipsrhinitis, fibromyalgia, and chronic fatigue

    Posted by Deborah on 6/23/10

    Good one. Thanks, Sharon.

    On 6/21/10, Sharon wrote:
    > Relationships among rhinitis, fibromyalgia, and chronic
    > fatigue
    > 1/00000003/art00002
    > Authors: Baraniuk, James N.; Zheng, Yin
    > Source: Allergy and Asthma Proceedings, Volume 31, Number
    > 3, May/June 2010 , pp. 169-178(10)
    > Publisher: OceanSide Publications, Inc
    > Allergy and Asthma Proceedings is a peer reviewed
    > publication dedicated to distributing timely scientific
    > research regarding advancements in the knowledge and
    > practice of allergy, asthma and immunology. Its primary
    > readership consists of allergists and pulmonologists.
    > The goal of the Proceedings is to publish articles with a
    > predominantly clinical focus which directly impact quality
    > of care for patients with allergic disease and asthma.
    > Featured topics include asthma, rhinitis, sinusitis, food
    > allergies, allergic skin diseases, diagnostic techniques,
    > allergens, and treatment modalities. Published material
    > includes peer-reviewed original research, clinical trials
    > and review articles.
    > Abstract:
    > New information about the pathophysiology of idiopathic
    > nonallergic rhinopathy indicates a high prevalence in
    > chronic fatigue syndrome (CFS). This article shows the
    > relevance of CFS and allied disorders to allergy practice.
    > CFS has significant overlap with systemic hyperalgesia
    > (fibromyalgia), autonomic dysfunction (irritable bowel
    > syndrome and migraine headaches), sensory hypersensitivity
    > (dyspnea; congestion; rhinorrhea; and appreciation of
    > visceral nociception in the esophagus, gastrointestinal
    > tract, bladder, and other organs), and central nervous
    > system maladaptations (central sensitization) recorded by
    > functional magnetic resonance imaging (fMRI). Neurological
    > dysfunction may account for the overlap of CFS with
    > idiopathic nonallergic rhinopathy. Scientific advances are
    > in fMRI, nociceptive sensor expression, and, potentially,
    > infection with xenotropic murine leukemia-related virus
    > provide additional insights to novel pathophysiological
    > mechanisms of the “functional” complaints of these patients
    > that are mistakenly interpreted as allergic syndromes. As
    > allergists, we must accept the clinical challenges posed by
    > these complex patients and provide proper diagnoses,
    > assurance, and optimum care even though current treatment
    > algorithms are lacking.
    > Keywords: Central sensitization; CFS; chronic fatigue
    > syndrome; dysautonomia; fatigue; fibromyalgia; idiopathic
    > nonallergic rhinitis; pain; xenotropic murine leukemia-
    > related virus; XMRV
    > Document Type: Research article
    > DOI: 10.2500/aap.2010.31.3311

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