Follow us!

    Post: 2, 3-DPG and nitric oxide

    Posted by Pat on 4/09/03

    Before I posted on Dilnaz's discovery that MCS sufferers
    have excess 2,3-DPG enzymes due to extreme oxygen deprivation.

    As I've also posted b4, Martin Pall put forth the theory of
    NO. poisoning as the etiology of MCS. I contacted Martin
    Pall and asked him how nitric oxide (NO) could explain the
    2, 3-DPG excess. He wrote, "Nitric oxide binds to heme
    groups just as does carbon monoxide. Having said that, I
    would think that there are other, more plausible mechanisms
    by which nitric oxide might produce increases in 2,3-DPG
    including the vasodilatation produced by nitric oxide,
    leading to increased pooling of blood in the lower parts of
    the body and decreased perfusion in other tissues."

    Posts on this thread, including this one

  Site Map:  Home Chatboards Legal Jobs Classified Ads Search Contacts Advertise
  © 1996 - 2013. All Rights Reserved. Please review our Terms of Use, Mission Statement, and Privacy Policy.
The Counsel.Net ChatBoardsm. All Rights Reserved.