Re: Hey Pat: About nitric oxide

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Hey, how r ya?

That is a good question and at present I'm not sure. I think more
research should take place before any conclusions are drawn.

The data on MCS's origins and mechanisms is overwhelming. For example,
Albert Donnay has a competing theory a CO poisoning as a cause of
chemical sensitivity. Excessive levels of CO will increase levels of
NO via iNOS. "Marty?s theory is just one little slice of what CO
poisoning does to people", said Donnay,

Interestingly, stresses of all kind (emotional, chemical, etc)
increase CO levels via HO-1. This could explain why emotional stress
often heightens sensitivity in sufferers.

However, the genetic data point more to a NO etiology. I think the two
work together to certain degrees depending on the case.

The NO/CO pathways should definitely be the focus of research.

I think that until more data are collected, the answer to your
question would have to be speculative and I don't like speculation.

Take care,

~ Pat

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