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    Re: Pres of ACOEM responds to WSJ Article

    Posted by Sharon on 1/25/07

    MBobMean,

    I don't know anything about the NSC. However, the document you
    cite is authored by the principals of Veritox:

    Coreen A. Robbins, Ph.D., CIH, Lonie J. Swenson,CIH, William
    T.Geer, CIH, and Bruce J. Kelman, Ph.D., DABT

    This is the same litigation defense support corp that authored
    the ACOEM Mold Statement.

    NO ONE besides this corp has professed to be able to establish
    human threshold/dose indicative of human mycotoxin exposure
    within a water damaged building by using extrapolations founded
    upon data from rodent studies. Their findings in this matter
    have been replicated by NO ONE ELSE.

    You can't do. Among other reasons, with a primary reason being
    is that when humans are exposed to mycotoxins within a water
    damaged building, the toxins enter the body via all three
    routes of exposure simultaneously. So to do an inhalation study
    of mice and attempt to corrolate that to the human situation is
    irrelevant.

    Also, when humans are exposed to mycotoxins within water
    damaged buildings, they are exposed to several (along with
    other microbial contaminants) simultaneously. Therefore the
    threshold/dose would change for each mycotoxin because the
    other variables involved would change the level of mycotoxins
    that would cause ill health. Not well worded, but the data
    would need to be lowered for each toxin as there is alot going
    on within the body and the building when water damage/mold is
    involved that can't be studied simply by instilling one type of
    mycotoxin into the lungs of mice/rats.

    And different molds have different weights. You can't study
    Stachy and conclude aspergillus. So to use the genertic
    term "mycotoxin" does not apply equally for all mycotoxins. The
    dose relevant for humans to become ill from mycotoxins/molds
    within a water damaged building is an indeterminable number.

    Rodent studies are very valuable though. While they can't
    establish dose, they do help to understand what the human
    symptoms are when mycotoxins are within the body.

    Sharon


    On 1/25/07, MBobMean wrote:
    > Actually Sharon, the NSC published a brief review that echos
    > teh findings of the ACOEM. I have never found the NSC to be
    > corporate shills or doubters, simply people concerned with
    > what could and could not be established. See it at:
    >
    > https://secure.nsc.org/public/issues/mold.pdf
    >
    > Also, the ACOEM acknowledges some potential health effects
    > from mold exposure:
    >
    > "A growing body of literature associates a variety of
    > diagnosable respiratory illnesses (asthma, wheezing, cough,
    > phlegm, etc.), particularly in children, with residence in
    > damp or water-damaged homes (see reviews 3-5). Recent
    > studies have documented increased inflammatory mediators in
    > the nasal fluids of persons in damp buildings, but found
    > that mold spores themselves were not responsible for these
    > changes.6,7 While dampness may indicate potential mold
    > growth, it is also a likely indicator of dust mite
    > infestation and bacterial growth. The relative contribution
    > of each is unknown, but mold, bacteria, bacterial
    > endotoxins, and dust mites can all play a role in the
    > reported spectrum of illnesses, and can all be minimized by
    > control of relative humidity and water intrusion."
    >
    > Why are you being so hard on them? They're simply
    > explaining the state of the available evidence. I wasn't
    > impressed with the WSJ piece, I don't think newspaper
    > reporters typicall--regardless of how exhaustive they say
    > their reserach is--are terribly accurate or qualified, and I
    > certainly agree that the evidence to date is lacking for
    > many of the cause and effect associations that have
    > been "hinted at" in many case reports, but that molds are
    > certainly, or certainly can be, allergens and sensitizers
    > and make people sick.
    >
    > What's so terribly wrong with that?
    >
    > mbobmean

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